If you have read some of our previous articles on cannabis and its vast range of beneficial compounds called cannabinoids, you are probably already familiar with the two dominant ones called CBD and THC. We have also touched upon the less-popular and somewhat hidden in the shadows cannabinoids such as CBN, CBT, CBCV, CBGM, and more.

While CBD and THC prevail in the cannabis world, they are certainly not the only important compounds to pay attention to. All of cannabis’ cannabinoids have the power to work wonders in the human body thanks to the endocannabinoid system that each and every one of us has.

The Endocannabinoid System

The endocannabinoid system comprises of receptors such as CB1 and CB2 receptors, which are responsible for different functions essential for the body. For example, it is exactly these receptors that we can attribute our mood and appetite to, our sleeping patterns, and even our motor functions. CB1 and CB2 receptors do have their own unique set of characteristics and are found in different parts of the body but the important fact is that cannabinoids can successfully communicate with them, stimulating different activities.

Some cannabinoids will stick to CB1 receptors more, while others will communicate predominantly with CB2 receptors. Based on this, researchers can establish which cannabinoids can influence certain health conditions, such as anxiety or depression, nausea, cancer, Parkinson’s disease, and more.

CBE or Cannabielsoin

As one of the least researched cannabinoids found in cannabis, cannabielsoin remains a mystery and little information is available on the topic. You will probably not find any CBE products on the market, in contrast to CBD, for instance. Countries, where cannabis has been legalized for medical purposes, offer consumers products such as CBD oil, CBD tinctures, or CBD edibles. The case with CBE is something else.

The cannabinoid was first discovered from researchers working in the Ohio State University in 1983. What is interesting about the compound is that it is used for the formation of cannabidiol or CBD via a metabolic process, which transforms cannabielsoin into a metabolite. CBE became of particular interest to the Japanese Hokuriku University. The researchers were intrigued by the biological mechanism that was part of the process behind the transformation of cannabielsoin into cannabidiol.

Unlike THC (the psychoactive substance of cannabis, which is mainly responsible for the high effect after consumption), CBE will not trigger any psychotropic effects once consumed and will not expose consumers to mind-altering experiences.

Where can we find CBE?

CBE or cannabielsoin can be found in cannabis sativa and certain cultures of Saccharum officinarum. However, in order to be found within these plants, there must be optimum growth conditions available. An interesting fact is that the compound has also been seen in guinea pigs’ liver. The researched pig went through an intraperitoneal administration of cannabis before the discovery of the compound was made.

The test showed that no change in temperature was caused as a result of the substance and there was no registered effect of pentobarbital-induced sleep.

Cannabielsoin Properties

As mentioned earlier, the compound will not produce any psychoactive effects once consumed and will therefore not trigger euphoria or hallucinations – conditions which may be extremely dangerous for patients suffering from certain diseases affecting the mind.

Studies from the 1980s discovered that CBD triggered the creation of cannabielsoin as a new metabolite. In terms of the characteristics of the compound, researchers have classified it as an aromatic hydrocarbon, ether, an industrial by-product or pollutant, a lachrymator, pesticide, organic compound, and synthetic compound.

More research is required on cannabielsoin alone to fully describe the compound and establish its effects on the body.

The Entourage Effect

Although no research is available on cannabielsoin suggesting any medical benefits of the compound for the human body, when mixed with other cannabinoids, cannabielsoin may have a therapeutic influence on the body, which is yet to be researched. The Entourage Effect suggests that when consumed in combination, cannabis’ cannabinoids have the power to provide an enhanced effect in the body.

Each cannabinoid has diverse abilities but when consumed together, the cannabinoids form a special synergy which may help treat certain health conditions quicker and more efficiently.

The world of cannabis is extremely intriguing, deep, and the more we research into the topic, the more we can start to understand the true potential of the plant. Nature does, in fact, provide a remedy for health conditions that medicine struggles with and sophisticated technology are allowing researchers to dig deeper into the matter.

If you have decided to try a cannabis-related treatment for a specific health condition, it is advisable to arrange a consultation with your doctor or a medical professional who can provide legitimate advice and guide you through the process. 



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